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ПРОФИЛАКТИКА ПРОГРЕССИРОВАНИЯ АНЕМИИ БЕРЕМЕННЫХ С ПРИМЕНЕНИЕМ СИРОПА СПИРУЛИНЫ «VITASPIRUM»
стр.7-10
Аникин С.С., Заболотнов В.А., Рыбалка А.Н.
Experience of using of the syrup containing a live spirulina for the purpose of prevention anemia of pregnant women is analyzed. The analysis of the domestic and world literature on the studied problem is carried out. The most effective modes of daily dispensing and duration of therapy are offered and proved.
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СТАН НОВОНАРОДЖЕНИХ ВІД МАТЕРІВ З ПЕРЕНОШЕНОЮ ВАГІТНІСТЮ
стр.11-13
Біволаріу А.О., Каліновська І.В.
Важнейшая проблема современной перинатологии - снижение перинатальной смертности и болезней детей. Патологическое течение беременности, особенно перенашивание, вызывает нарушение гомеостатических механизмов материнского организма, результатом чего является гипоксия плода и развитие в постнатальном периоде разных форм полиорганной недостаточности. Перинатальная патология при плацентарной дисфункции проявляет себя формированием повреждений центральной нервной системы (ЦНС) как самого чувствительного органа к гипоксии. В статье представлен клинико-статистический анализ 50 беременных с переношенной беременностью и анализ состояния новорожденных от данной группы матерей. Наиболее тяжелые формы перинатальных повреждений ЦНС у новорожденных, которые родились в сроке гестации 41-42 недели формируются в результате развития плацентарной дисфункции. В раннем неонатальном периоде адаптация новорожденных детей от матерей в сроке 41-42 недели с проявлениями плацентарной дисфункции протекает с клиническими признаками гипоксии. Анамнестическое исследование репродуктивной функции показало, что для этой группы беременных характерны репродуктивные потери, которые обусловлены привычным невынашиванием у 22 женщин (44%), предыдущими медицинскими абортами - у 13 (26%). В анамнезе у 8 пациенток (16%) в предыдущих беременностях определялись тяжелые или осложненные формы гестоза, угроза прерывания беременности - у 21 женщины (42%), токсикоз первой половины беременности - у 7 женщин (4%). Таким образом, клинические проявления перинатальных поражений ЦНС новорожденных зависят от степени тяжести плацентарной дисфункции.
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ВЛИЯНИЕ БАЛЬНЕОГРЯЗЕЛЕЧЕНИЯ НА ПОКАЗАТЕЛИ ГОРМОНАЛЬНОЙ РЕГУЛЯЦИИ У ЖЕНЩИН С БАКТЕРИАЛЬНЫМ ВАГИНОЗОМ
стр.14-18
Болдырева О.А., Рыбалка А.Н., Каладзе Н.Н.
The objective: to study the influence of pelotherapy on indicators of hormonal regulation in women with bacterial vaginosis. Conducted a study of indicators of hormonal regulation in 186 women with bacterial vaginosis using ELISA method: 128 women with normal prolactin level and 58 women with hyperprolactinemia. A study of the dynamics of laboratory data under the influence of pelotherapy. The mud treatment has a stimulating effect on adrenal function, modulating effect on the level of the pituitary and sex hormones in women with bacterial vaginosis and normal prolactin levels. It was revealed worsening of hormonal imbalance in women with bacterial vaginosis and hyperprolactinemia: the higher initial levels of prolactin, disorders of the pituitary and ovarian regulation. There is a need for a differentiated approach to mud treatment of gynecological patients with hormonal disorders taking into account the level of prolactin.
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ОСОБЕННОСТИ СОСТОЯНИЯ ЭНДОТЕЛИЯ РОГОВИЦЫ У ПОСТРАДАВШИХ В ОТДАЛЕННЫЕ СРОКИ ПОСЛЕ КОНТУЗИОННОЙ ТРАВМЫ ГЛАЗА И ПРОГНОЗИРОВАНИЕ РИСКА ЕЕ ПОВРЕЖДЕНИЯ
стр.19-21
Голубов К.Э., Баринов Э.Ф.
Contusion injury of the eye results to quantitative and morphological changes of the endothelium. They are manifested by changes in corneal thickness in the Central division, the reduction in the density of endothelial cells, and a decrease in the number hexagonally cells. Installed factor the features that determine the risk of disorders of the corneal endothelium. Early administration of exogenous phosphocreatine leads to the reduction of the risk of post-concussion disorders of the corneal endothelium the standardization of patient status for all risk factors.
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Первый опыт применения стромальных клеток КОСТНОГО МОЗГА в терапии экспериментальной туберкулезной инфекции женских половых органов
стр.22-26
Гусейнова Ф.М., Ниаури Д.А., Виноградова Т.И., Юдинцева Н.М., Муртузалиева А.А., Блюм Н.М., Момот Д.С., Заболотных Н.В., Витовская М.Л., Кольцова Т.В., Яблонский П.К.
The objective of the study was to evaluate the efficacy of mesenchymal stem cells (MSC) in complex therapy of experimental female genital tuberculosis in rabbits. It is indicated that the injection of MSC (in concentration 5 million/ml) under the serous tunic of the left uterus tube, decrease the reaction of tissue in response to experimental tuberculous infection, limit the outcome to infiltrative and cicatrical adhesion in the inflammatory response, show estimate positive influence on reparation, increase functional activity of peritoneal macrophage.
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НОВЫЕ ПОДХОДЫ В ПРОФИЛАКТИКЕ ВРОЖДЕННЫХ ПОРОКОВ РАЗВИТИЯ И НАСЛЕДСТВЕННЫХ ЗАБОЛЕВАНИЙ ПЛОДА
стр.27-29
Демидова Н.С., Заболотнов В.А., Рыбалка А.Н.
360 pregnant women with high risk of development the congenital malformations (CM) and hereditary diseases (HD) had been examined. The 1 main group included 160 women, who were the subject of our developed method of prevention. For comparison was the 2 group, which consisted of 160 women, whose pregnancy was carried out on the basis of a common, standart method and national clinical protocols. The III control group included 40 women, who refused from our own, and the traditional methods of prevention. We proposed the method of prevention CM and fetal HD which is significantly more effective than common, standard principles of controlling (monitoring)the pregnancy with high risk of development the CM and fetal HD.
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ХАРАКТЕРИСТИКА ТЕЧЕНИЯ АДАПТАЦИОННОГО ПЕРИОДА У НОВОРОЖДЕННЫХ, РОЖДЕННЫХ ОТ ЖЕНЩИН С ИЗБЫТОЧНОЙ МАССОЙ ТЕЛА
стр.30-36
Дука Ю.М., Нагорнюк В.Т., Хало М.В.
The analysis of the adaptation period at 278 newborns who were given rise by pregnant women with various body weight is provided in article. At dynamic supervision of newborns in the neonatal period signs and indicators which characterized features of adaptation were considered: maximum loss of body weight, edematous syndrome, course of neonatal jaundice, condition of cardiovascular system, glycemia, bilirubin level. It is proved that the condition of the children born from mothers with an excess weight deserves special attention not only during prenatal development, but also after the delivery.
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ВЛИЯНИЕ ИММУНОТРОПНЫХ ПРЕПАРАТОВ НА КЛИНИЧЕСКИЕ ПОКАЗАТЕЛИ У ПАЦИЕНТОВ С СУХОЙ ФОРМОЙ ВОЗРАСТНОЙ МАКУЛЯРНОЙ ДЕГЕНЕРАЦИИ
стр.37-40
The immunotropic therapy influence to clinical parameters in 108 patients with dry form of age-related macular degeneration was studied. There was an increase in visual acuity at 41,5±5,7%, the field of vision expanded to 3,1±0,1%. critical frequency flicker fusion level increased to 19,3±1,3%, electrical sensitivity retinal by phosphene level (p
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ПРИЧИНЫ КЕСАРЕВА СЕЧЕНИЯ ПРИ ПРЕЖДЕВРЕМЕННЫХ РОДАХ
стр.44-47
Зиядинов А.А., Сулима А.Н., Рыбалка А.Н.
The analysis of the incidence of premature labour was carry out. The features and indications of operative delivery.were defined. The causes of caesarean section in preterm labor were determined.
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БЕЗОПАСНЫЙ АБОРТ: ЗА И ПРОТИВ
стр.48-51
Иванов И.И., Черипко М.В., Косолапова Н.В., Прочан Е.Н.
The article summarizes the history of interruption pregnancy in women who applied for a medical abortion at the clinic “Female Welfare Center”, Simferopol, during the first quarter of 2015. A higher incidence of side effects and complications after medical abortion in comparison to vacuum aspiration abortion has been revealed at high efficiency (96,7% and 100,0%, respectively) of the two methods.
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применение ЛИПОФЛАВОНА для коррекции цитокинового дисбаланса У БОЛЬНЫХ ХРОНИЧЕСКИМ НЕСПЕЦИФИЧЕСКИМ КОНЪЮНКТИВИТОМ
стр.52-55
ИВАНОВА Н.В., Короткова Е.Ю.
Influence of flavonoid-lipoflavon (ophthalmic drops) in the experiment in vitro in patients with chronic conjunctivitis and imbalance of proinflammatory cytokines investigated. There is an activation of the system of local immunity, which is a pathogenetic substantiation of flavonoid-lipoflavon application in the complex treatment of patients with chronic conjunctivitis.
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ЭФФЕКТИВНОСТЬ ПРИМЕНЕНИЯ ФЛАВОНОИДА (КВЕРЦЕТИНА) В ЛЕЧЕНИИ ДИАБЕТИЧЕСКОГО МАКУЛЯРНОГО ОТЕКА
стр.56-60
ИВАНОВА Н.В., Ярошева Н.А., Ярошева Л.М.
It is known that the number of patients with diabetes mellitus steadily grows. Also physical inability from this pathology, especially from its complications where the first place on frequency vascular angiopathy occupy, to which carry also diabetic retinopathy (DR) essentially grows. At quercetin (lipoflavon) application in the complex treatment of patients with DR normalization of a calibre of microvessels begins on 4 days faster, reduction of microhemorrhages - on 6 days faster, reduction of edema macula - on 5 days faster, than at ordinary complex therapy. At application of the complex therapy with quercetin (lipoflavon) an index of threshold sensitivity of retina on 28,1% more than at treatment by traditional therapy. At application of quercetin (lipoflavon) in the complex treatment efficacy of resorption of macular edema has appeared in 3,7 times higher, than at treatment by traditional therapy. The received results of investigation testify about larger efficacy of application of quercetin for treatment of diabetic macular edema in the complex treatment of patients with DR.
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Сердечно -сосудистые эффекты пролактина у детей с артериальной гипертензией
стр.61-64
Каладзе Н.Н., Ревенко Н.А.
We conducted a complex study of the of 72 children with primary hypertension. Identified functional hyperprolactinemia, most pronounced in stable hypertension while maintaining gender-specific hormone secretion in the pre- and puberty. Higher levels of prolactin in children with metabolic disorders in contrast to children with normal body weight due to the metabolic effects of the hormone secretion and its adipose tissue. Enhanced understanding of the functional hyperprolactinemia as a risk factor of hypertension and metabolic syndrome. The mechanisms of action of prolactin in view of its metabolic effects. The practical value in eating disorders, sleep and physical activity in children with hypertension for the formation of hyperprolactinemia.
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ИЗМЕНЕНИЕ УРОВНЕЙ ПОЛОВЫХ ГОРМОНОВ У БОЛЬНЫХ ЮВЕНИЛЬНЫМ РЕВМАТОИДНЫМ АРТРИТОМ КАК ФАКТОР ПАТОГЕНЕЗА ЗАБОЛЕВАНИЯ
стр.65-70
Каладзе Н.Н., Соболева Е.М., Скоромная Н.Н.
In patients with juvenile rheumatoid arthritis revealed changes in the content of sex hormones, depending on age, sex, disease activity, duration of the disease. Decrease of peripheral sex hormones level (testosterone - in boys, estrogens and progesterone -in girls), affects the formation of disease symptoms, hyperprolactinemia is a factor of formation and progression of the disease.
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ОСОБЛИВОСТІ УЛЬТРАЗВУКОВОЇ КАРТИНИ СТРУКТУР ЕМБРІОНА, ПЛІДНОГО ЯЙЦЯ ТА ХОРІОНА У ВАГІТНИХ З НЕВИНОШУВАННЯМ
стр.71-74
Несмотря на большое количество работ, направленных на изучение невынашивания беременности, данная проблема остается актуальной. Частота данной патологи продолжает оставаться ведущим патогенетическим звеном репродуктивных потерь. Поэтому изучение проявлений первичной плацентарной недостаточности у беременных с невынашиванием в ранние сроки является актуальным и способствует снижению перинатальной смертности. Проведено исследование эхографических изменений эмбриона и эмбриональных структур и хориона у беременных с проявлениями плацентарной дисфункции на фоне невынашивания в анамнезе. Данные показатели имеют прогностическое значение для вынашивания беременности и ее перспективности. Размеры эмбриона и плодного яйца являются прогностически значимыми критериями отягощенного течения беременности. Это свидетельствует о необходимости проведения ультразвукового исследования с оценкой эхографических параметров становления и развития эмбриона и экстраэмбриональных структур у беременных с риском развития плацентарной дисфункции и невынашиванием в анамнезе
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Клиническая значимость определения HLA-B27 у пациентов с передними эндогенными увеитами
стр.75-77
Копаенко А.И., ИВАНОВА Н.В.
The study included 348 patients (365 eyes) with anteriоr endogenous uveitis (AEU), which were treated at the Crimean Republican Center of Eye Microsurgery from 2008 to 2013. Determined, that HLAB27- associated AEU accounted for 41% of total AEU cases in the Crimean population. This necessitates including HLA-B27-test in examination standards of patients with AEU. HLA-B27-associated AEU were in 1.9 times more common in men, than in women. In patients with HLA-B27-positive AEU inflammatory reaction in the anterior chamber 3+ and 4+ was 2 times more often, inflammatory process was recurrent in 4 times more often, macular edema was in 1.5 times more often, mean visual acuity was on 0.21 less than in patients with idiopathic AEU (p
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ВЫБОР МЕТОДА РОДОРАЗРЕШЕНИЯ БЕРЕМЕННОСТИ, НАСТУПИВШЕЙ В РЕЗУЛЬТАТЕ ПРИМЕНЕНИЯ ПРОЦЕДУРЫ ЭКСТРАКОРПОРАЛЬНОГО ОПЛОДОТВОРЕНИЯ
стр.78-80
Ляшенко Е.Н., Румянцева З.С., Прочан Е.Н., Могоровская А.В., Насырова Э.Р.
To study the features of the selection method of delivery pregnancy was the result of in vitro fertilization investigated 184 cases of pregnancy after assisted reproductive technology. Presented evidence for the management of labor vaginally provided that the studied cohort of pregnant isolated male or tubal factor infertility, and indications for a planned abdominal delivery. The study found that pregnant after in vitro fertilization frequency of operative delivery is 90,22% and significantly higher than in normal childbirth.
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ТИРЕОИДНАЯ ФУНКЦИЯ БЕРЕМЕННЫХ С ЙОДНЫМ ДЕФИЦИТОМ В ПЕРВОМ ТРИМЕСТРЕ ГЕСТАЦИИ
стр.81-83
In this work we study the thyroid status of pregnant women with iodine deficiency in the first trimester of pregnancy. It was founded that 60% of pregnant women with this disorder have a minimal thyroid insufficiency (fT3/ fT4≥0,28), even with the normal recommended level of excretion of thyrotropic hormone within 2,5 mMЕ/L. The most severe thyroid dysfunction observed in pregnant women with antibodies to thyroid peroxidase.
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ОЦЕНКА ФАКТОРОВ РИСКА И ВНУТРИКЛЕТОЧНОЙ ПРОДУКЦИИ IL-10 МОНОЦИТАМИ ПЕРИФЕРИЧЕСКОЙ КРОВИ И МАКРОФАГАМИ ДЕЦИДУАЛЬНОЙ ОБОЛОЧКИ ПРИ ЗАДЕРЖКЕ РОСТА ПЛОДА
стр.84-86
Милеева П.Л., Малышкина A.И., Бойко Е.Л., Сотникова Н.Ю., Воронин Д.Н.
At inspection of pregnant women with a of fetal growth retardation by us have been identified the following risk factors: smoking, a chronic genyantritis, chronic pyelonephritis, endometriosis, neurocirculatory dystonia, abortions, infertility, the migrated surgery on the uterus and appendages, inflammatory diseases of the genitals, diffuse enlargement of the thyroid gland; at pregnancy: exacerbation of chronic of pyelonephritis, arterial hypertension pregnancy-induced, respiratory diseases in the II trimester of, threat of interruption in the I and II trimester of. Fetal growth restriction in pregnancy increases the risk of adverse outcomes in children. Decrease in IL-10 production in placental macrophages is associated with an inflammatory process, may be an important link in the pathogenesis of fetal growth retardation.
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К ВОПРОСУ О ЦЕЛЕСООБРАЗНОСТИ ПРОИЗВОДСТВА ТАЗОВОЙ ЛИМФАДЕНЭКТОМИИ ПРИ РАКЕ ЭНДОМЕТРИЯ I СТАДИИ
стр.87-89
Мирович Е.Е., Мирович Е.Д., Шаганов П.Ф.
The surgery of 82 patients with endometrial cancer I stage in the amount of hysterectomy with appendages, pelvic lymphadenectomywere done. Found that performing of lymphadenectomy surgery for endometrial cancer of the I stage leads to a significant increasing of duration of operation and anesthesia, and also increases the number of postoperative complications. However, metastases in thelymph nodes were found only in 3,7% of the cases, which raises doubts about the appropriateness of lymphadenectomy.
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ГЕМОДИНАМИКА ГЛАЗНОЙ АРТЕРИИ У НЕДОНОШЕННЫХ НОВОРОЖДЕННЫХ ДЕТЕЙ
стр.90-92
Николаева Г.В., Сидоренко Е.И.
Doppler examination of the ophthalmic artery was performed in children at risk of retinopathy of prematurity (ROP) in the neonatal period. The study included 21 children (42 eyes) with average gestational age 28,6±1,4 weeks and average birth weight - 1187±244 g. It was found that the blood flow in ophthalmic artery had spastic nature: resistance index (IR) was 0,79±0,04, peak systolic velocity (Vmax) was 14,6±8,0 cm/sec, diastolic flow velocity (Vmin) 2,9±1,5 cm/sec. There was a significant increasing of systolic blood flow velocity during the first week of life, p
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ГЕСТАЦИОННАЯ АДАПТАЦИЯ И МЕТАБОЛИЧЕСКИЙ СИНДРОМ
стр.93-99
Попов А.Д., Чегус Л.А., Чёрная Е.Е.
Studied parameters of homeostasis, the state of adaptation mechanisms and nonspecific resistance at the stages of pregnancy in 154 women with obesity and 90 - underweight. Complex clinical and laboratory techniques have revealed the nature of the hypothalamic changes in body weight. The control group was 107 pregnant women with normal weight-height correlation. Screening of pregnant women includes a study of metabolic parameters, evaluation of adaptive reactions, the study of daily excretion of catecholamines, colonization resistance, serum lysozyme activity and β-lysine, α-1-antitrypsin and α-2-macroglobulin. At the surveyed patients during pregnancy revealed different adaptive strategies: excessive and prolonged sympathetic-adrenal activation in women with altered body weight throughout gestation, in the control group expressed less stress coping mechanisms was observed only in the first and third trimester. Gestational complications, metabolic status and dissonance disbiotic nonspecific resistance factors significantly more frequently recorded in the study group. It is advisable to carry out activities for the enhancement of adaptive responses in women with obesity and underweight in step preconception preparation.
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КОМПЛЕКСНОЕ ЛЕЧЕНИЕ ДЕВОЧЕК С УРОГЕНИТАЛЬНОЙ ИНФЕКЦИЕЙ
стр.100-102
Попова-Петросян Е.В., Довгань А.А., Брауде И.Е.
The aim of the study is to determine the efficacy of Hibisci flores in the treatment for cystitis caused by chlamidia infection. We conclude that addition of Hibisci flores in the standard treatment for clamidiosis substantially improved clinical manifestation and has resulted by complete recovery in 80% of all cases.
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РЕПРОДУКТИВНОЕ ЗДОРОВЬЕ ЖЕНЩИН ПОСЛЕ ЭНДОХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ ТРУБНОЙ БЕРЕМЕННОСТИ
стр.103-107
Рыбалка А.Н., Аникин С.С., Сулима А.Н.
The thesis contains a generalization and a new solution of scientific problem in the field of obstetrics and gynecology devoted to restoration of reproductive function in women after endosurgical treatment of ectopic pregnancy. In order to solve this problem several diagnostic methods (clinical, sonographic, radiological, hormonal, bacteriological, bacterioscopic and statistical) as well as multi-stage treatment and rehabilitation measures were proposed. 195 women with ectopic pregnancy were enrolled in the study, the control group had 25 healthy women.
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ОСОБЕННОСТИ ТЕЧЕНИЯ И ТЕРАПИИ ВИРУСНЫХ ПНЕВМОНИЙ У БЕРЕМЕННЫХ
стр.108-112
Рыбалка А.Н., Егорова Я.А., Заболотнов В.А.
Pneumonia is one of the most common human diseases. The incidence of pneumonia in pregnant women does not differ from the incidence in the general population. However, in pregnant women, it poses a serious threat not only to the health of women, but also for the future of the child. We have clinical and statistical analysis of the course of viral and viral-bacterial pneumonia in 24 obstetric patients. Material for the study served as the medical history of pregnant women who were in the maternity hospital in the period from 2010 to 2014. The complex of conservative treatment, including not only antibacterial, and antiviral drugs would lead to positive results in the treatment of pneumonia in pregnant women with a minimum of perinatal loss. However, at the present time, modern medicine due to objective reasons are not sufficiently effective in the fight against severe influenza complicated by hemorrhagic pulmonary edema or brain.
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ПЕРИТОНЕАЛЬНЫЕ ТАЗОВЫЕ СПАЙКИ У ЖЕНЩИН РЕПРОДУКТИВНОГО ВОЗРАСТА: ДИАГНОСТИКА И ТАКТИКА ЛЕЧЕНИЯ
стр.113-116
Рыбалка А.Н., Сулима А.Н., Аникин С.С., Алексеев А.А.
The thesis paper is aimed at decreasing the frequency of reproductive function disorders in women with pelvic peritoneal adhesions by investigating new aspects of the pathogenesis of this disease, as well as to develop an advanced algorithm for diagnostic, therapeutic, preventive and rehabilitative measures. This paper expands the understanding of the pathogenesis of adhesions in the pelvis associated with the study of the role of proinflammatory cytokines and immune CD68-positive cells (macrophages) in the tissues of the pelvic peritoneal adhesions in women at reproductive age. It has been proved that peritoneal fluid imposes a pronounced influence on the development of adhesions as well as that the peritoneal fluid constitutes the most significant increase in the content of proinflammatory cytokines. Based on the accumulated clinical material which attests the effectiveness of different methods of topical diagnosis of abdominal and pelvic organs adhesions in women of reproductive age. The scientific work presents and justifies the selection of algorithm for surgical approach depending on the location of adhesions in the abdominal cavity and the type of operation. It suggests the pathogenetically proved prevention of adhesions and offers a differentiated approach to the management of patients with pelvic peritoneal adhesions, while taking into account the risk, effectively reducing the likelihood of recurrence and improving the long-term outcomes (reduction in the number and density of adhesions in the pelvis) among the patients who underwent surgical treatment.
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ОФТАЛЬМОПАТИЯ (РЕТИНОПАТИЯ) НЕДОНОШЕННЫХ - ПРОБЛЕМА НА ВСЮ ЖИЗНЬ
стр.117-119
Analysis of the state of the visual analyzer was conducted on the basis of long-term studies of the Department of Ophthalmology Pediatric Faculty of Russian National Research Medical University named after N.I. Pirogov. We focused on the problems that accompany a child after recovering from retinopathy of prematurity as long as life endures.
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СВОБОДНОРАДИКАЛЬНОЕ ОКИСЛЕНИЕ ЛИПИДОВ И АНТИОКСИДАНТНАЯ АКТИВНОСТЬ У БЕРЕМЕННЫХ С НЕДИФФЕРЕНЦИРОВАННОЙ ДИСПЛАЗИЕЙ СОЕДИНИТЕЛЬНОЙ ТКАНИ ПРИ НЕДОНОШЕННОЙ БЕРЕМЕННОСТИ
стр.120-122
Ситникова О.Г., Парейшвили В.В., Назаров С.Б., Вахромеев А.П., Кузьменко Г.Н., Попова И.Г.
The study included 25 pregnant women with undifferentiated dysplasia of connective tissue in gestational ages 22-36 weeks antenatal discharge of amniotic fluid (first study group) and 25 pregnant women with undifferentiated dysplasia of connective tissue in gestational ages 22-36 weeks without prenatal outpouring of water. In the first control group included 25 pregnant women with no signs of undifferentiated dysplasia of connective tissue prenatal rupture of water in the gestational ages of 22-36 weeks. The second control group included 15 pregnant women without systemic pathology of connective tissue with physiological pregnancy in terms 22-36 weeks. It is established that undifferentiated connective tissue dysplasia in patients in preterm pregnancy was accompanied by increased lipid peroxidation and increased antioxidant activity.
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ПРОВЕДЕНИЕ ПРОГРАММ ВСПОМОГАТЕЛЬНЫХ РЕПРОДУКТИВНЫХ ТЕХНОЛОГИЙ ПО ТРАНСПОРТНОЙ СХЕМЕ С ДОНОРСКИМИ ВИТРИФИЦИРОВАННЫМИ ООЦИТАМИ
стр.123-126
Сулима А.Н., Литвинов В.В., Яковенко С.А.
A five-year experience in assisted reproduction technologies with eggs donation on transport scheme in сlinic «Vash Doctor», Simferopol - сlinic «Altra Vita», Moscow were described in this paper.
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РОЛЬ НАСЛЕДСТВЕННЫХ И ПРИОБРЕТЕННЫХ ТРОМБОФИЛИЙ В ПАТОГЕНЕЗЕ САМОПРОИЗВОЛЬНОГО АБОРТА И привычной потери БЕРЕМЕННОСТИ
стр.127-131
Харкевич О.Н., Миров А.И.
The aim of this research was studying of role of trombofiliya in pathogenesis of spontaneous abortion and habitual loss of pregnancy. Clinical, laboratory and tool methods of research were applied. In total 102 patients were examined. From them 27 - habitual loss of pregnancy, 46 - with a single spontaneous abortion or with not developed pregnancy and 29 women of control group who took out pregnancy twice without essential complications. The condition of system of a hemostasis was estimated in 25 parameters by the standard techniques. The statistical analysis of results is made by means of the computer software package of STATISTICA (version 7.0) with use of methods of nonparametric statistics. Various thrombophilia was diagnosed for 19,2% of patients of the main groups (more than one thrombophilia - at 5,5%). At the patients with habitual loss of pregnancy various thrombophilia came to light more often and made - 33,3% (more than one thrombophilia - 10,9%). Also multicomponent changes of a hemostasis at patients with a thrombophilia were revealed, which took place in the middle of the second phase of a menstrual cycle. Results of research indicate an important role of a thrombophilia in pathogenesis of spontaneous abortion and habitual loss of pregnancy.
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ОСОБЕННОСТИ ГИНЕКОЛОГИЧЕСКОГО И СОМАТИЧЕСКОГО СТАТУСА В ПУБЕРТАТНОМ ПЕРИОДЕ
стр.132-134
Хуцишвили О.С., Ангалева Е.Н.
A total of 169 girls who applied to the gynecologist, aged 10 to 18 years. Of these, one in three - 54 (31,9%) - had pubertal age women with an abnormal uterine bleeding. In 42,5% of them on the background of underweight observed lag pubertal - Tanner stage 3. 48,0% of the patients showed a trend toward later becoming menarche. A significant was the fact that in the absence of organic pathology of the endometrium in girls with pubertal uterine bleeding have a high incidence (77,7%), psycho-emotional, autonomic disorders and somatic pathology. It is assumed that complex therapy of abnormal uterine bleeding will contribute to the normalization of autonomic disorders and recovery of menstrual function in most cases.
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СОВРЕМЕННЫЕ АСПЕКТЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ ПИЕЛОНЕФРИТА У БЕРЕМЕННЫХ
стр.136-137
Чермных С.В., Слюсарь Т.И., Шпатусько Н.И., Джеломанова О.А.
On the basis of complex inspection of 130 pregnant women (58 - healthy women, 72 - with acute pyelonephritis) and their newborns it is revealed that pyelonephritis at pregnant women are accompanied by endogenous intoxication, SIRS, against which violations of all links of a homeostasis develop. Inclusion of a plasmapheresis in a complex of medical actions promotes fast decrease in markers of endogenous intoxication, normalization of hemostasis indicators, immunity, function of organ’s and systems of a natural detoxication, outcomes for mothers and babes.
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ТАКТИКА ВЕДЕНИЯ БЕРЕМЕННЫХ С ТЕРМИЧЕСКИМИ ПОРАЖЕНИЯМИ КОЖНЫХ ПОКРОВОВ В ЗАВИСИМОСТИ ОТ ТРИМЕСТРА БЕРЕМЕННОСТИ
стр.138-140
Чурилов А.В., Фисталь Э.Я., Кушнир С.В., Михайличенко В.Ю., Джеломанова С.А.
The article presents classification of burn injuries based on lesion depth in female patients on different gestational age. The proposed classification of burns based on lesion depth includes emergent pathophysiological mechanisms and anatomical relationships of tissues, which provide more objective assessment of clinical picture, and expect outcomes. Based on suggested classification the management of pregnancy follow-up was developed depending on trimester of pregnancy. The main and controversial issue of management of burned pregnant women is concerning on abortion or maintenance of pregnancy and also on the best terms and methods of abortion.
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МАРКЕРЫ ПРОЛИФЕРАЦИИ И АПОПТОЗА ПРИ НАРУЖНОМ ГЕНИТАЛЬНОМ ЭНДОМЕТРИОЗЕ
стр.145-149
Маркарьян И.В., Ермолова Н.В., Линде В.А., Мажугин В.Ю., Друккер Н.А., Колесникова Л.В., Томай Л.Р., Слесарева К.В., Скачков Н.Н.
The review of literary dates about markers of proliferation and apoptosis in ectopic and eutopic endometrium and their value in pathogenesis of endometriosis and endometriosis-associated infertility is submitted. Data on an expression of receptors of an estrogen and a progesterone, markers of proliferation, apoptosis, adhesion, an angiogenesis, cellular invasion are submitted.
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ВАРИКОЗНАЯ БОЛЕЗНЬ ВЕН МАЛОГО ТАЗА КАК ПРИЧИНА ХРОНИЧЕСКОЙ ТАЗОВОЙ БОЛИ
стр.150-156
Рыбалка А.Н., Миклин О.П., Камилова И.К., Косолапова Н.В., Прочан Е.Н., Гудзь О.В.
The article summarizes the main idea of the chronic pelvic pain syndrome and about one of the most common reasons for it - varicose veins of the pelvic organs, given current recommendations for diagnosis, differential diagnosis and treatment.
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